Considering that tens of millions of individuals now take statins to lower cholesterol, the following headline was conspicuously missing from the major media this month: “Statins Found to Turn On Gene that Causes Muscle Damage.” It’s now a fact of science; a new study shows that taking statins destroys your muscle to a greater or lesser degree. Furthermore, let’s not forget that the heart is a muscle. Place this study compared to another rather interesting recent finding: the fitter you are the longer you will live – and the two just don’t add up. How can you destroy muscle and be more fit? You can’t. Sure you can drug your cholesterol number lower, but will you be healthier, fit, and live longer?
In the new study researchers found that statins activate a gene signal in muscles called atrogen-1. When this gene activates it targets key muscle proteins for destruction. The activation of this gene drives the process of muscle atrophy and muscle wasting. It is induced in cardiac muscle in failing hearts. Why on earth would any person want this gene activated by a drug? The researchers tested statin-taking humans who were complaining of severe muscle pain. Muscle biopsy found that the atrogen-1 gene was activated, in comparison to people with severe muscle pain not on statins and controls. They went on to show through various experiments that statins activate the gene. This is extremely bad news for any person taking a statin..
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